[11C]Carfentanil

 

JML Products

 

Carfentatnil precursor

 

 

Radiosynthesis description:

 

Reaction scheme

Comment

One step reaction can be accomplished in-loop or in-vessel.  Product can be isolated using either HPLC or SPE.1-3

References

1.         Dannals, R. F. et al. Radiosynthesis of an opiate receptor binding radiotracer: [11C]carfentanil. International Journal of Applied Radiation and Isotopes 36 [4], 303-306 (1985).

2.         Jewett, D. M. A simple synthesis of [11C]carfentanil using an extraction disk instead of HPLC. Nuclear Medicine and Biology 28 [6], 733-734 (2001).

3.         Studenov, A. R., Jivan, S., Buckley, K. R. & Adam, M. J. Efficient In-Loop Synthesis of High Specific Radioactivity [11C]Carfentanil. Journal of Labelled Compounds and Radiopharmaceuticals 46 [9], 837-842 (2003).